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Omega-3's Counterpart

Omega-3's have dominated EFA supplement sales until now.

Source: Nutritional Outlook
Date Published: October, 1999

Essential Fatty Acids (EFA) are garnering international attention for their possible beneficial effects on arthritis, skin conditions and cardiovascular afflictions. While Omega-3 EFA supplements are widely popular among consumers, its counterpart, Omega-6 EFAs have been virtually ignored, according to Artur Klimaszewski, an MD with Biorigianl Food and Science Corp., Saskatoon, Saskatchewan, Canada, manufacturer of EFAs.

There are four types of Omega-6 EFAs: Linoleic Acid (LA), Gamma-linolenic Acid (GLA), Dihommagamma-linolenic Acid (DGLA) and Arachidonic Acid (AA). "LA is the most common form of Omega-6. It is found in vegetable oils such as corn, sunflower, soybean and safflower oils," says Klimaszewski. "While these sources are commonly found in foods people eat every day, the problem lies with the Delta-6 Desaturase (D6D) enzyme needed to metabolize LA. In many people, this enzyme is impaired due to changing environmental conditions and high consumption of hydrogenated fat. "This damage can be attributed to genetic impairments as well as environmental and lifestyle factors, such as high intake of foods containing LA, alcohol consumption, aging, disease conditions and stress, he says.

AA, found mainly in meats, eggs and shellfish, is found to produce a class of eicosonoids that constricts blood vessels and subsequently increases the possibility of blood clotting. DGLA is found only in human milk and in small quantities in some organ meats such as spleen, liver and kidney.

These factors have influenced researchers to focus their attention on GLA, which bypasses the D6D enzyme and doesn't require it for metabolism. There are three natural sources of GLA: borage oil, also known as star flower, containing 20-24 percent GLA; black currant oil, containing 14-17 percent GLA; and evening primrose oil, containing 8-10 percent GLA. "Borage and black current oils are good sources because the public is more familiar with it than the other two sources," says Klimazewski.

The GLA Solution

Once in the body, GLA produces a class of eicosanoids that are anit-inflammatory, dilate blood vessels and reduce blood clotting, says Klimaszewski. These effects are helpful in the treatment of arthritis, skin conditions such as eczema and psoriasis, lowering and even preventing high blood pressure and reducing blood clotting, which can lead to heart attacks and strokes. While he doesn't want to create false hopes, "preliminary studies have shown that GLA can help increase survival time in certain cancer patients and slow down the growth of cancerous tumors," Klimaszewski adds.

GLA can be used topically on the skin or taken orally. Because the oils are sensitive to light, heat and oxygen, the oral supplements are often sold in soft gelcaps. Health From the Sun had added a line of EFA supplements to its product line to meet the growing interest in the products. The supplement line, contract manufactured by Bioriginal, includes straight evening primrose, borage and black current oils, formulas that are mixed with Omega-3s, mixed formulas of borage oil that target specific disorders such as "heart formula" and "EFA Attention Formula" that is positioned to help people with attention deficit disorders and "Total EFA."

"Each product has found its own segment of demand," says David Kulow, president, Health From the Sun, Waltham, MA. While each of the supplements can be used by all adults, Kulow had found the products are primarily being purchased by females. The primrose has been well received "because it has been associated with more hormonal and skin issues," says Kulow. The black current oil has been received well too. Even though it tends to be more expensive that the other two oils, due to special machinery needed to extract the oil, it contains both Omega-6 and Omega-3 EFAs.

October 1999
Nutritional Outlook

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