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Gamma Linolenic Acid may help rheumatoid arthritis patients move more freely


MEDFORD, MASS, May 2000 - New research confirms that the right fats can help loosen the joints of people suffering from rheumatoid arthritis.

A recently completed report on the therapeutic value of Gamma Linolenic Acid (GLA) confirmed that this essential fatty acid may be an important addition to the diets of rheumatoid arthritis patients.

The review was completed by the medical research firm, Metaworks, Inc. in Medford Mass.

Lead researcher Dr. Marya Zilberberg reports that GLA is not only safe, but it is also an effective natural therapy. In her review of close to 40 clinical papers on GLA, Zilberberg noted that GLA consistently reduces inflammation and joint stiffness without any of the serious side effects associated with pharmaceutical drugs. "GLA certainly appears to have a much more favorable side effect profile than any of the drugs on the market for rheumatoid arthritis. You are not seeing any of the problems that those other drugs seem to cause," said Zilberberg.

Zilberberg found that GLA is particularly useful for reducing morning stiffness. "We saw about a 60-65 per cent reduction in morning stiffness for these patients," said Zilberberg. "In other words if you have two hours of morning stiffness, that goes down to about a half hour. It is an extremely striking difference."

This is good news for rheumatoid arthritis patients who often see morning stiffness as the most debilitating effect of their disease.

"If you were to ask a rheumatoid arthritis patient about morning stiffness you would find that it is an extremely important indicator of how their disease is doing." said Zilberberg.

Severe cases of rheumatoid arthritis can lead to weight loss and permanently disfigured joints. Other complications include morning stiffness, night pain and dependence on nonsteroidal anti-inflammatory drugs (NSAIDs).

NSAIDs include aspirin, ibuprofen, naproxen and others. These drugs provide pain relief, but can cause side effects in thousands of patients who use them long-term. Common side effects include abdominal pain, diarrhea, bloating, heartburn and upset stomach. Close to 30 per cent of patients on long-term NSAID treatment develop ulcers of the stomach. Animal studies show that GLA also provides an anti-ulcer effect by protecting the stomach lining from gastric acid. Observations published in Annals of Rheumatoid Disease (vol. 47, 1988) indicate that patients can reduce their dependence on NSAIDs by adding GLA to their treatment regimens.

Dr. Ronald Lawrence, an assistant clinical professor at the UCLA School of Medicine in Los Angeles, is currently working to find a safe treatment for degenerative arthritis. He has begun to use GLA on some of his arthritis patients. "My patients say that they move freer and easier and seem to be more relaxed, sort of lubricated if you will. That's nice to hear because stiffness is a big problem with all types of arthritis but particularly rheumatoid arthritis."

GLA is an essential fatty acid found in the seeds of plants such as borage and evening primrose. This quiet cousin to popular fish and flaxseed oils has yielded positive results in a number of studies including rheumatoid arthritis, skin conditions such as eczema, diabetic neuropathy and coronary heart disease. Borage oil, also known as starflower oil, is the richest natural source of GLA, and is available in health food stores and pharmacies across North America. Clinical research done in the last 10 years indicates that an effective dosage of GLA for rheumatoid arthritis is found in 3 to 10 grams of borage oil per day. Results are generally seen within 4 to 12 weeks of supplementation.

- Source: Metaworks Inc., Medford, Mass.

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